I just can’t help it. I don’t have any choice in the matter . . .
Something is prodding at me to write a kick ass theme framework using currently supported HTML5, CSS3, JS libraries, and a nice grid layout framework.
The plan is to build the framework and use it for client sites for a while in house, and in the course of doing so, learn which options would be useful to WordPress designers and developers, while offering the most flexibility and creative freedom.